(sold as Advair Diskus in the US)
and fluticasone propionate
and Product :
Each Diskus contains 60 Blisters.
(Advair Diskus) Seretide Accuhaler -- 100-50mcg/dose (containing
fluticasone propionate 100micrograms with salmeterol
(Advair Diskus) Seretide Accuhaler -- 250-50mcg/dose (containing
fluticasone propionate 250micrograms with salmeterol
(Advair Diskus) Seretide Accuhaler -- 500-50mcg/dose (containing
fluticasone propionate 500micrograms with salmeterol
Seretide Accuhaler (Advair Diskus)
Generic ingredients: Fluticasone propionate, Salmeterol
Why is this drug prescribed?
Seretide Accuhaler (Advair Diskus) is an oral inhaler that
contains two types of asthma medication. One is fluticasone
propionate, a steroid that reduces inflammation in the lungs.
The other, salmeterol, is a long-acting bronchodilator that
opens up the airways. Together, the two ingredients provide
better control of asthma than either does individually.
Most important fact about this drug
Seretide (Advair) is used for long-term control of asthma,
and won't end a sudden attack. For relief of acute asthma
symptoms, your doctor will prescribe a short-acting inhaler such
as Proventil or Ventolin.
How should you take this medication?
Seretide Accuhaler (Advair Diskus) should be used twice a
day, once in the morning and once in the evening. Follow the
detailed directions that came with the inhaler. If you have any
questions, ask your doctor or pharmacist. Some important points
to keep in mind:
- Do not use a "spacer" with this medication.
- Never exhale into the diskus.
- Do not try to take the diskus apart.
- Always activate and use the diskus in a level, horizontal
- It is important to keep the diskus dry--do not wash any
part of the mouthpiece or any part of the diskus.
- To reduce the risk of developing an infection in your
mouth, rinse your mouth after each inhalation.
When first using this medication, you may notice some
improvement within 30 minutes, but its maximum benefits may take
a week or more to appear.
--If you miss a dose...
Take it as soon as you remember. If it is almost time for
your next dose, skip the one you missed and go back to your
Store the diskus at room temperature, away from heat,
sunlight, and moisture. Discard the diskus one month after
removing it from its moisture-protective foil overwrap pouch or
after every blister has been used, whichever comes first.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change
in intensity, inform your doctor as soon as possible. Only your
doctor can determine if it is safe for you to continue taking
- More common side effects may include:
Bronchitis, cough, diarrhoea, difficulty speaking, fungal
infection of the mouth, gastrointestinal discomfort and pain,
headaches, hoarseness, muscle pain, nausea, sinus problems,
sore throat, upper respiratory infection or inflammation,
- Less common side effects may include:
Allergic reactions, appendicitis, blood in nasal mucus, bone
problems, burns, constipation, dental discomfort and pain, dry
and scaly skin, ear problems, eye infection, fractures, heart
palpitations, hives, joint pain, lower respiratory infections,
mouth ulcers or rash, mouth discomfort or pain, muscle
injuries, muscle stiffness, nasal irritation, nerve problems,
red eyes, runny nose, pneumonia, skin infections, sleep
disorders, sleepiness, sneezing, sweating, tremors, wounds
Why should this drug not be prescribed?
(Seretide) Advair cannot be used for acute episodes of asthma
that require intensive therapy. You'll also have to avoid it if
it gives you an allergic reaction.
Special warnings about this medication
Be sure to keep track of how often you have to use your
short-acting inhaler for relief of acute asthma symptoms. Your
doctor will use this information to help determine how well
Advair Diskus is working. Notify your doctor if you do not get
relief from your short-acting inhaler or if you need more
inhalations than usual to get relief. Keep track of your peak
flow readings, too. Call your doctor if you notice a drop in
this measurement of lung capacity.
Do not use Advair Diskus more often than your doctor has
prescribed. Excessive use can cause heart irregularities. Use
Advair Diskus with caution if you have any kind of heart
disorder or high blood pressure. Alert your doctor immediately
if you develop chest pain, heart palpitations, nervousness, or
Do not use Serevent (salmeterol), Foradil (formoterol), or
other long-acting inhalers while using Advair Diskus. They
contain the same type of active ingredient, and will provide no
Call your doctor immediately if you develop hives, rash, or
swelling, or if you have an asthma attack that does not respond
to your usual medication. Advair Diskus has been known to cause
allergic reactions and acute asthma attacks.
Try to avoid contact with people who have measles or
chickenpox, and notify your physician if you are exposed. The
steroid component of Advair Diskus tends to lower your immunity
and could make these infections worse.
Possible food and drug interactions when
taking this medication
If Seretide Accuhaler (Advair Diskus) is used with certain
other drugs, the effects of either could be increased,
decreased, or altered. It is especially important to check with
your doctor before combining this medication with the following:
Antidepressants categorized as "tricyclics," such as Elavil and
Antidepressants called "monoamine oxidase inhibitors," such as
Nardil and Parnate
Beta blockers (drugs such as Inderal and Tenormin that are used
to control blood pressure and treat various heart conditions)
Long-acting inhalers such as Serevent and Foradil
Water pills (diuretics) such as HydroDIURIL and Lasix
Special information if you are pregnant or
The possibility of harm to a developing baby has not been
ruled out. Seretide Accuhaler (Advair Diskus) should be used
during pregnancy only if the potential benefit justifies the
It is possible that the ingredients of Advair Diskus may
appear in breast milk, so you'll need to choose between nursing
the baby or continuing your therapy.
The recommended dosage of Seretide Accuhaler (Advair Diskus)
is one inhalation twice daily. Take the inhalations morning and
evening, 12 hours apart.
The product comes in three strengths. Your doctor will select
the best strength for you based on your current therapy. If this
selection fails to improve your asthma after 2 weeks, the doctor
may prescribe a higher strength.
Seretide Accuhaler (Advair Diskus) can be used by adolescents
12 years of age and older. The dosage is the same as for adults.
It is not known whether this medication is safe for children
under 12. Its steroid component has been known to stunt growth.
Any medication taken in excess can have serious consequences.
If you suspect an overdose, seek medical attention immediately.
- Symptoms of acute Seretide Accuhaler (Advair Diskus)
overdose may include:
Fast or irregular heartbeat, headache, muscle cramps, tremor